I don't think I ate at many new restaurants (newly opened in 2008) this year. Among the few:
Mixteco Grill (Chicago/North Center?) - liked it a lot
Takashi (Chicago/Wicker Park) - was disappointed
I'm not sure when these opened but they may have opened in 2008, but maybe were around before that:
Mundial Cocina Mestiza (Chicago/Pilsen) - liked it a lot, my best Mexican meal of the year
Big Jones (Chicago/Andersonville) - liked it a lot (for brunch)
Jesse's Mexican Grill (Chicago/Rogers Park) - liked it a lot, my go-to place for conventional Mexican food
Di Pescara (Northbrook) - just okay