There is another recent thread on Charleston, so perhaps the moderators can combine.
Here is the report from my wonderful trip there this past weekend:
Magnolias: Had dinner there. An excellent introduction to upscale low country cooking. I enjoyed the low country bouillabase. Not my favorate place, but a good meal.
Hominy Grill: A half hour wait for lunch (was supposed to be 50 minutes), but worth it. I had a vegetarion plate, which collards, lima beans, and tomato and okra stew on rice. The okra stew was the best. My wife loved her shrimp and okra beignets. Basically, go with anything okra. My wife had the she crab soup, a local speciality. It was just O.K. Highly recommended.
Bowen Island Restaurant: You need a car to get there and it takes about 20 minutes, but its the highlight of any trip. A large shack type place on the water. Go for the steamed oysters, $14 at tray for $28 for all you can eat. It's a weird type of oyster that comes in a big clump of multiple shells. Some clumps are dud with nothign but mud, some have a few very tiny oysters, and a few times you hit a proper sized one. But eat morsel was simply the sweetest, tastiest oyster I've ever had, and the atomsphere can't be beat. Just a mob of people drinking beer and eating oysters and fried seafood.
SNOB: A good example of the modern low county cuisine (along with McCradys, Cypress, FIG and Husk). My dish typifies what they are doing: Quail breast stuffed with cornbread and tasso, and two little quail legs deep fried in a buttermilk coating. All served over collards. Vibrant atmosphere and good cooking.
Farmer's Market: If you are there on a Saturday morning, go the the square with the Calhoun statutes (the name escapes me at the moment) for a wonderful market with lots of cooked foods to eat, as well. You walk around the park and they have produce as well as local craftspeople. Plan to have your breakfast there.
Hope that helps. If you want any tips on sights to see just ask.