Just my opinion from two visits in December... that the two restaurants of A Mano and Bin 36 are the embodiment of brother and sister. The details:
I've always been a fan of Bin 36, not so much for their food, but for wine flights, cheese, and appetizers. Then I heard that they recently opened up another place right below them, A Mano, which aspires to an Italian trattoria and focus on the meats and authentic Italian rather then the wines + cheeses- I guess it's the younger brother. Besides the good selection of cured meats, A Mano's food are light bites of pasta, pizzas, and panini, and they do more substantial entrees for dinner. A Mano has wine by the glass and bottle, not flights, and the menu doesn't describe them as enthusiastically as the sister restaurant
I went to both, and I still prefer Bin 36 for a more casual spot if I'm looking for a place to chat and have a drink and a bite, not a whole dinner because I think you can do better for a real meal, despite the more impressive entrees at A Mano. The salumi at A Mano are indeed excellent, but I was not that impressed by the pastas that everyone else has been raving about. When I had the Pumpkin Ravioli with brown butter, black walnuts, brussels sprout leaves, and Pecorino Gran Cru, I found it only so so. I expected the filling to have had more flavor, like they needed to season the filling just a little bitfor punch- otherwise this dish admittedly was otherwise prepared perfectly well.
The Risotto Valpolicella with wild mushrooms and Taleggio cheese was a tad salty, and although the mushrooms were good, I didn't like that they were so large. If it had been some sort of meat, I would have been fine with the size, but if there are veggies in the risotto, I want them a size that doesn't require a knife.
The Gnocchetti with sweet butter and Parmigiano Reggiano was light and fluffy and melt in your mouth, but were not the best gnocchi I've ever had (A Tavola still has that honor). It was subtle and sweet, yet I felt like it was still missing something to take it to the next level.
At A Mano, the antipasto of salumi I selected was Culatello – “Little Rump” Ham. I was disappointed they didn't have the one I wanted to try the first time I was there, the Mole Salami which would have been spiced- they were sold out! However, they did have it on a Sunday evening, and both meats were smooth and super tasty. The other antipasto was Baby Dandelion Greens, Roasted Peppers, Capra Honey Goat Cheese, Lemon Vinaigrette, was a mix: the goat cheese was really good. The greens however, had too much vinaigrette and it soured the mini-salad.
Also, I tried the gelato/sorbetto offerings. I was able to select from half a dozen different flavors, and I chose the orange prosecco (which was disappointing- I expected more prosecco flavor), mascarpone (just for balance), and hazelnut chocolate (which was the best of the bunch). Definitely go for hte gelatos over the sorbettos.
Surprising, the best dish of the night was the entree (only available at dinner- everything else you can get at lunch as well) of “Black Pig”- or at least that's how it rang up on the check! This is the entree of Slow Roasted "Black Pig Chop," Braised Apples & Endive. This chop is HUGE- you can see it is more than an inch think, width wise it is probably 5 inches and length wise 7 inches. Burstingly juicy with a good balance of meat and a hint of fat (even if not full of flavor, look at all that juice it waits so soak up at the bottom of the platter), I could taste the complexity and traces of bacon. I was sorry I could only eat 1/4 of this monster. Some old lady even came up to hug me because she saw me facing this thing on my own, and later came up to check on me to see how I progressed. This is the best pork chop I have ever had, and at $24 it is priced right, assuming you are willing to spend $24 on just an entree (hey, it is like 3 meals, cuz you will take some of this baby home).
Service the first time I went (for lunch) was painfully slow for no reason. The second time I was waited by the person at the bar (despite being at a table just on the other side where the two waitresses were working) and she was wonderful after I was left waiting a while for water and a menu at first. I should note that I went on two off times (Mon lunch, Sun dinner) so I could see them chatting with each other as they worked in the open kitchen. To sum it up, the highlights of A Mano was... an appetizer of meat and an entree of meat for $8 + $24. HA ha, see it is the brother restaurant!!
On the other hand, despite the poor service at Bin 36 for lunch (one guy seemed to be waiting on the whole section and I sadly ate all the breadsticks on the table while waiting, and the breadsticks aren't even that good!), I really felt it met my expectations better. The cheese plate below was incredible. My self-selected cheese flight consisted of for sheep a Brin D'Amour, Chantal Plasse, Corsica, France (”Smothered with herbs, this cheese is a chef's favorite. Maybe it's the rich, pizza-like flavor?“ It totally was my favorite cheese too, it had so much complex flavor!), a goat cheese which was ok but not memorable, and for cow the Burrata, Puglia, Italy (“This one is only delivered twice a month, so when we have it, get it! Mozzarella-like on the outside with plenty of sweet cream curds on the inside”). Out of 3 visits to the place, this is only the first time I was able to get it, which probably built my expectations too high- it got the mozz down but I thought it would be sweeter.)
To compliment my Chardonnay flight, I ordered Duo of Crepes, mixed greens, sherry vinaigrette . The brown one is the porcini with wood grilled mushrooms, gruyere and lemon creme fraiche , very earthy, while the yellow crepe is the chive with truffled potato confit, marissa cheese, white truffle butter. It was light and delicious, I wish I could have had more of it.

A Mano's Culatello – Little Rump Ham

salumi of mole salame

A Mano's pumpkin ravioli

Risotto Valpolicella, Wild Mushrooms, Taleggio Cheese

Gnocchetti, Sweet Butter, Parmigiano Reggiano

Black Pig

A Mano's gelatos and sorbetto

Cheese plate at Bin 36

Crepe lunch at Bin 36