I first heard Lustig interviewed on a People's Pharmacy broadcast last November. I was stuck in traffic and flipping channels. I stopped when I heard the topic. I have a personal interest in that I have always been a little heavy, was in the biomedical field decades ago and recognized that as I age I might be on the track toward metabolic disease or diabetes, and I want to avoid diabetes if at all possible. About a decade ago I learned that fructose was not metabolized in the same tissues or by the same pathways as glucose, and I suspected HFCS might be involved in the US trend toward obesity and diabetes and may have implications for my own health.
It is for that reason I listened to the People's Pharmacy show last November, and later sat thru a 90 minute seminar Lustig presented to his colleagues at the UC San Francisco Medical School in July, 2009.
I nearly posted something on this topic then, but hesitated, not knowing whether it would be accepted/appreciated. I'm glad the OP got this started.
Rather than risk a poor presentation of Lustig's findings, I direct you to the resources I found so you may listen or view and decide for yourselves. I think it is more helpful to listen to Lustig yourselves than to listen to an interpretation compiled by the media.
The November 2011 People's Pharmacy radio show is still up on their site. It is available to listen to or download free. I suggest downloading the 'Extended' or 'Bonus' interview. I have compared it to the original show and find that it is 'Extended' by virtue of having been edited less. I found the 'Extended' interview more informative, and because it flowed better, easier to follow.
http://www.peoplespharmacy.com/2011/11/ ... r-hazards/Further down the page is a link to Lustig's UCSF seminar in 2009 on YouTube. I found the entire presentation exceptionally well done. While Lustig's talk covered history, politics, clinical findings, etc., I found myself focused on about 20 minutes of biochemistry in the middle of the presentation where he made the comparison of the metabolism of fructose to that of ethanol. Lustig demonstrates that the pathways are similar, as are the diseases which are the consequence of over use of each (by example, he states that high consumption of fructose can result in sclerosis of the liver, as does high consumption of ethanol).
http://www.youtube.com/watch?v=dBnniua6-oMI think Lustig and others on this trail may be on to something. Lustig's work, and the work of others who's findings are similar, will not be vetted by this board. Rather, I think that people on this board may find themselves interested as Lustig's findings may impact choices individuals make and may be central to future national discussions of public health.
Enjoy (as I did)