Deep dish pizza (and Chicago style thin crust pizza with homemade Italian sausage) is a passion for me, and in my very humble opinion, Louisa's in Crestwood is probably the best I've ever had. The late Louisa DeGenero worked as a waitress and a cook at Pizzeria Due for over 2 decades. Her adult daughter, who runs Louisa's today, also worked at Pizzeria Due for at least 10 years. Her crust is slightly buttery, but not as buttery as Lou Malnati's or Pizano's. It's a shallower/thinner version of Pizzeria Due, with some of the best toppings in America, and the world for that matter.
Louisa's tomatoes are excellent, and similar to Lou Malnati's in taste, but not quite as chunky as Lou Malnati's. The family grows their own Italian herbs and spices behind the restaurant in the summer months, which perfectly compliment Louisa's tomatoes. Her garlic sausage is made in house, and is some of the best sausage you'll ever have on a pizza of any style. It's very heavy on the garlic, with some cracked black pepper, and other Italian seasonings. Louisa's housemade sausage is every bit as good as the garlic sausage used at Burt's Place, the Anichini Brothers garlic sausage used at Pizano's and Pizzeria Uno/Due, and the garlic sausage from Peoria Meat Packing that supplies Lou Malnati's. And if you like onions, Louisa's uses the same style of long, carmelized onions that Pizzeria Uno/Due still uses, as opposed to the more square cut versions at Lou Malnati's and Pizano's, although I think Pizano's small, square cut onions are the best.
For appetizers, try the Chicken Vesuvio wings in garlic, olive oil, and white wine sauce. For dessert, they offer Italian ice served in a full lemon with the top cut off, and the lemon ice inside. If my memory serves me correctly, I think Louisa's uses some of the same black cast iron pans from the old days at Pizzeria Due, too.
The service is o.k.- not bad, but nothing great, either. They're just there when you need them. And that's good enough for me, especially when we're talking about some of the best deep dish pizza anywhere. We're talking destination pizza here, and one of Chicagoland's true culinary gems.
Good stuff.