I travel US 30 between I 69 and I 75 fairly often and the best I come up with is Taco Bell--so eat before you get to Fort Wayne.
I did have a killer breakfast at a little diner in Nelsonville about 60 miles SW of Columbus on US 33. (From my CH post: "Real biscuits and great home fries (huge portions); the pies looked amazing." ) And that's a pretty area of Ohio to ride thru if you have the time...
The Coffee Cup Restaurant
615 Washington St. (US 33)
Nelsonville, OH
740-753-3336
And to suggest yet another detour, passing the giant windmills just West of Bowling Green on US 6 was pretty cool--they're right next to the road.
Have a safe trip!